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Genetics (Hereditary Disorders)

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Gene constraint and novel variants associated with canine orofacial clefts and stature
Oct 11, 2025 Whole-genome sequencing and gene-constraint analysis

Gene constraint and novel variants associated with canine orofacial clefts and stature

Whole-genome sequencing of multiple dog breeds links PDGFRA, CSF1, LCORL, and ITGA11 variants to orofacial clefts and stature, advancing canine

Key Finding: Splice-acceptor variant in PDGFRA gene discovered in Çatalburun dogs with bifid nose
dogs
5 min read Genome Research

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