Dogs Fed Pea-Rich Diets Show Signs of Reduced Heart Efficiency

Study finds pea-based diet reduced stroke volume/output and increased nt-probnp vs. grain diet in dogs.

Journal: PLOS ONE
Sample Size: 8 adult Beagle dogs
Study Type: Controlled feeding trial (28-day diet crossover)
Published: 2023-05-24
Species:

Key Findings

  • Pea-based diet reduced stroke volume/output and increased NT-proBNP vs. grain diet
  • Lower protein/amino acid digestibility; blood methionine decreased
  • Lentil-based grain-free diet did not show short-term cardiac changes

Pea-Rich Grain-Free Dog Diets Linked to Early Heart Changes, Study Finds

Introduction

Many dog owners have turned to grain-free diets, believing they are healthier options for their pets. However, recent concerns have surfaced about the safety of these diets—especially those loaded with pulses like peas and lentils. A new study published in PLOS ONE sheds light on why pea-rich, grain-free dog foods may deserve a closer look, particularly for breeds at risk of heart disease.

Understanding what goes into your dog’s bowl is more important than ever. With diet-associated heart conditions making headlines, this research offers timely evidence about the potential effects of certain grain-free diets on canine heart health.

Research Background

Veterinarians have noted an uptick in cases of dilated cardiomyopathy (DCM), a serious heart condition, among dogs eating grain-free foods high in pulses such as peas and lentils. While previous studies have shown a correlation, there’s been a lack of controlled trials pinpointing which ingredients or mechanisms might be responsible.

This new research stands out because it directly compares the short-term effects of pea-rich and lentil-rich grain-free diets to a standard grain-based diet. By carefully controlling variables and monitoring heart health markers, the study aimed to clarify whether certain grain-free ingredients are driving early cardiac changes.

Study Details

Researchers conducted a 28-day controlled feeding trial using a crossover design. Here’s what you need to know about the study setup:

  • Subjects: 8 healthy adult Beagle dogs
  • Diet Phases: Each dog ate three diets in sequence:
    • Pea-based grain-free diet
    • Lentil-based grain-free diet
    • Grain-based control diet
  • Duration: 28 days per diet phase, with all dogs rotating through each diet
  • Measurements:
    • Echocardiography (to assess heart function, especially stroke volume and cardiac output)
    • Blood tests (including NT-proBNP, a marker of heart strain)
    • Digestibility assessments (for protein and amino acids)
    • Blood amino acid levels, focusing on methionine

This crossover approach allowed every dog to serve as its own control, improving the reliability of the findings despite the small sample size.

Key Findings

Primary Results

The results were clear: feeding dogs a pea-rich grain-free diet for just 28 days led to measurable, early changes in heart function compared to a grain-based diet.

  • Decreased Cardiac Output: Dogs on the pea-based diet showed a significant reduction in stroke volume (the amount of blood pumped with each heartbeat) and overall cardiac output. This means the heart was working less efficiently, even over a short period.
  • Increased NT-proBNP: Levels of NT-proBNP—a blood biomarker that rises when the heart is under stress—were elevated in dogs eating the pea-rich diet. High NT-proBNP is often used in veterinary medicine as an early warning sign of potential heart issues.

Secondary Findings

The study also uncovered nutritional differences that may help explain the observed cardiac changes.

  • Reduced Digestibility: Protein and amino acid digestibility were lower on the pea-based diet compared to the grain-based diet. This could mean dogs are absorbing fewer essential nutrients when eating pea-heavy foods.
  • Lower Methionine Levels: Blood concentrations of methionine, an essential amino acid important for heart health, dropped significantly in dogs fed the pea-based diet. Inadequate methionine could play a role in heart muscle function and disease risk.
  • Lentil-Based Diet: Interestingly, the lentil-based grain-free diet did not cause the same short-term changes in heart function or NT-proBNP levels as the pea-rich diet, suggesting not all pulses have identical effects.

Implications for Pet Owners

What This Means for You

If you’re feeding your dog a grain-free diet—especially one listing peas as a primary ingredient—this study suggests caution may be warranted. Even in just four weeks, pea-heavy diets caused early signs of cardiac strain and reduced nutrient absorption in healthy dogs.

Practical tips for pet owners:

  • Check the ingredient list: If peas are among the top ingredients in your dog’s food, consider discussing alternatives with your veterinarian. For dogs with sensitive digestion, a high-quality digestive supplement such as vegetarian digestive enzymes can help support nutrient absorption.
  • Choose AAFCO-tested diets: Select foods that have undergone feeding trials and meet established nutritional standards. When choosing treats, opt for single-ingredient options like freeze-dried beef liver dog treats that avoid unnecessary fillers and grains.
  • Monitor at-risk breeds: Breeds already predisposed to heart conditions (like Doberman Pinschers, Boxers, and Golden Retrievers) may be especially vulnerable to diet-associated DCM.

When to Consult Your Veterinarian

Always involve your veterinarian when making significant diet changes or if your dog is on a grain-free or pulse-heavy diet. Watch for signs of heart trouble, which can include:

  • Coughing, especially at night
  • Reduced exercise tolerance or fatigue
  • Rapid or labored breathing
  • Fainting or collapse

If you notice these symptoms, seek veterinary attention promptly. Your vet may recommend periodic cardiac screening, such as echocardiograms or NT-proBNP blood tests, especially if your dog is eating a grain-free diet. Supporting your dog’s gut health with organic probiotics may also help improve nutrient absorption when dietary digestibility is a concern.

Study Limitations

While this research provides important insights, it’s important to recognize its limitations:

  • Small sample size: Only eight Beagle dogs participated, which may not represent all breeds.
  • Short duration: The trial lasted just 28 days, so longer-term effects remain unknown.
  • Breed specificity: Results from Beagles may not directly translate to other breeds, especially those at higher risk for heart disease.

Further research with larger, more diverse groups of dogs and longer study periods will help clarify the full impact of pulse-rich diets on canine heart health.

Bottom Line

A short-term, pea-heavy grain-free diet triggered early signs of heart strain and reduced nutrient absorption in healthy dogs, while a lentil-based diet did not show the same effects. Not all grain-free diets are equal, and ingredients matter.

For pet owners:

  • Be cautious with diets that use peas as primary ingredients.
  • Opt for foods with established safety records and AAFCO testing.
  • Discuss dietary choices with your veterinarian, especially for dogs at risk of heart disease.
  • Consider periodic heart health screening if feeding a grain-free diet.

Diet is a cornerstone of your dog’s health. Staying informed and working with your veterinary team is the best way to keep your canine companion safe and thriving.

Based on the research findings discussed in this article, we’ve carefully selected these top-rated products to help you support your dog’s heart and digestive health. These products are chosen for their quality, customer satisfaction, and alignment with the scientific evidence presented.

Digestive enzyme supplement for dogs

Pure Encapsulations Digestive Enzymes Ultra

Digestive enzymes can help improve the breakdown and absorption of nutrients, supporting dogs that may experience reduced protein and amino acid digestibility on pulse-rich diets.
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Organic raw probiotics for digestive health

Wholesome Wellness Organic Raw Probiotics

Probiotics promote a healthy gut microbiome, which can improve nutrient absorption and overall digestive function for dogs on grain-free or pulse-heavy diets.
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Freeze-dried beef liver dog treats

Vital Essentials Beef Liver Dog Treats

Single-ingredient, high-protein treats are a healthy option for dogs needing grain-free rewards without added fillers, supporting overall nutrient intake.
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Purina ONE High Protein Natural Dry Dog Food

Purina ONE High Protein, Natural Dry Dog Food True Instinct With Real Turkey & Venison

An AAFCO-tested, grain-inclusive dog food formulated for complete nutrition and heart health, aligning with recommendations to avoid pea-heavy diets for at-risk breeds.
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Disclosure: We only recommend research-based products that support your pet’s health. As an Amazon Associate, we earn from qualifying purchases at no additional cost to you—helping us fund our mission to provide cutting-edge research to all pet lovers.

Disclaimer

This article summarizes peer-reviewed research for educational purposes. Always consult with your veterinarian for personalized advice about your pet’s health and behavior.

Reference

PLOS ONE. "Pea-Laden Grain-Free Diet Triggers Early Cardiac Changes in Dogs". PLOS ONE. 2023-05-24. DOI: 10.1371/journal.pone.0285381