Dog Gut Worms: 24.85% of Pet Dogs Test Positive in Haryana, India Survey
A survey of 310 pet and semi-pet dogs in Haryana, India found that 24.85% tested positive for zoonotic gastrointestinal …
Calcium Oxalate Stones in Dogs: A Human Drug Explored
A case report published in BMC Veterinary Research documents the off-label use of dapagliflozin, a human diabetes drug, in one dog with recurrent calcium oxalate stones. The drug did not reduce urinary calcium levels, was discontinued after 12 days due to underhydration concerns, and the authors concluded it may increase lithogenic risk if fluid intake is insufficient.
Key Findings:
- The report documents off-label use of dapagliflozin in a dog with recurrent calcium oxalate urolithiasis; the drug was discontinued after 12 days due to underhydration concerns.
- Urinary calcium-to-creatinine ratio remained elevated throughout treatment; glucosuria, acidic urine, and increased urine specific gravity developed.
- The authors concluded that short-term treatment did not reduce hypercalciuria and may increase lithogenic risk if fluid intake does not offset osmotic diuresis.
