Androgen-receptor glutamine repeat length influences vocalisation and aggression in domestic cats
Cats with short androgen-receptor alleles (≤18 repeats) show higher purring scores, with male carriers exhibiting more …
Gene constraint and novel variants associated with canine orofacial clefts and stature
Whole-genome sequencing of multiple dog breeds identifies a splice-acceptor variant in PDGFRA in Çatalburun dogs with bifid nose, a stop-gained CSF1 mutation in Chow Chows with unique skull shape, LCORL frameshift in large breeds, and ITGA11 frameshift fixed in small brachycephalic breeds. These variants clarify genetic links to morphology.
Key Findings:
- Splice-acceptor variant in PDGFRA gene discovered in Çatalburun dogs with bifid nose
- Stop-gained mutation in CSF1 gene linked to unique skull shape of Chow Chows
- Frameshift in LCORL gene associated with large breeds
- Frameshift in ITGA11 gene fixed in small brachycephalic breeds
